Flagship platformIn development

CLAIR / Veterinary oral health

Better evidence for canine dental triage.

CLAIR is a saliva-based adjunct in development for use alongside the oral examination. The proposed workflow combines collection, controlled processing on a centrifugal microfluidic disc, and optical readout to support triage and the owner conversation.

Development boundary: CLAIR is not for sale or clinical use. Analytical performance, workflow timing, and clinical utility remain to be established for each panel.

CLAIR platform / Veterinary programExplore human oral health ↗

01 / Intended role

Support the examination.
Explain the next step.

A saliva-based adjunct for the conversation about further dental assessment.

CLAIR asks whether a quantitative saliva panel can add useful evidence alongside the awake oral exam. The first planned setting is general veterinary practices with active dental services.

Clinical judgment remains central. CLAIR does not replace indicated dental assessment, probing, or radiographs. A low result must not delay otherwise indicated care.

02 / Proposed workflow

Collect. Process.
Read and interpret.

Conceptual collection swab, centrifugal cartridge, reader, and smartphone readout
Concept illustration, not final hardware or validated timing or performance.
  1. 01 / Sample

    Collection and validity

    Define oral collection and checks for sample quality.

  2. 02 / Disc

    Controlled handling

    Develop centrifugal processing, reaction control, and assay timing.

  3. 03 / Readout

    Structured interpretation

    Evaluate optical readout alongside the clinical context.

03 / Candidate saliva panel

Measure the signals.
Check the sample.

The combined panel and validity controls are a differentiation hypothesis. Multiplexing alone does not establish disease specificity.

Panel composition, thresholds, and interpretation require analytical and clinical validation. CRP remains a separate research track.

LDH
Candidate tissue-activity signal
MPO
Inflammatory activity
Phosphorus + pH
Oral chemistry context
Occult blood
Bleeding signal and potential interference
Sample validity
Collection and process controls

04 / Evidence before rollout

Three questions.
Three development gates.

Clinical added value remains unproven. Study size and timing depend on feasibility, a funded protocol, and statistical planning.

  1. 01

    Analytical readiness

    Can the panel measure reliably?

    Evaluate repeatability, interference, sample recovery, and collection and process controls. Report invalid samples.

  2. 02

    Independent clinical evaluation

    Does it add useful evidence?

    Compare the awake exam, panel alone, and exam plus panel against a blinded reference assessment using anesthetized probing and dental radiographs. Lock the panel and thresholds before independent validation and include realistic confounders.

  3. 03

    Customer validation

    Does it work for the clinic?

    Study workflow fit, owner understanding, willingness to pay, support needs, and repeat use with veterinary practices.

05 / Clinic collaboration

Help shape what
fits in practice.

The proposed first partners are general veterinary practices with active dental services.

Discuss clinic participation

Practice owners and managers

Evaluate workflow, purchasing, and operating fit.

Veterinarians and technicians

Evaluate collection, interpretation, usability, and training needs.

Dog owners and patients

The intended beneficiaries of clearer oral-health conversations.

Onboarding, interpretation guidance, troubleshooting, and consumable replenishment are proposed support needs. Reader, software, and per-test pricing require validation.

Platform foundation

Engineering experience.
Product-specific proof still ahead.

CLAIR draws on lab-on-disc, assay-development, imaging, kinetic-analysis, motor-control, and cartridge engineering experience. Manufacturing, quality-control, and regulatory and commercialization planning remain part of development.

Explore the scientific foundation
Intellectual property filing note

U.S. provisional application 64/126,200 was received August 5, 2026 for Portable Centrifugal Diagnostic Platform with Mobile-Device Optical and Kinetic Assay Analysis. A provisional filing is not an issued patent or a determination of patentability.